Understanding how a new protein helps maintain gut health and reduce inflammation
Official title: Defining a novel transcriptional regulator of intestinal health and inflammation
Funded at Weill Medical Coll of Cornell Univ · NIH-11009050 · Data updated 2026-11-12
This study is looking at a new protein that helps control how our immune system works in the gut, which could lead to better ways to manage conditions like inflammatory bowel disease (IBD) and keep our intestines healthy.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | January 8, 2024 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $90,000 |
| NIH project number | 5K99DK135923-02 |
| Project ID | NIH-11009050 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from inflammatory bowel disease or other gastrointestinal inflammatory conditions.
✕Less likely to help
Patients with non-inflammatory gastrointestinal disorders or those without any gastrointestinal issues may not benefit from this research.
What this research studies
This research investigates a newly identified transcription factor that plays a crucial role in regulating immune responses in the intestine. By studying how this protein affects various immune and stromal cells, the research aims to uncover mechanisms that promote intestinal health and prevent inflammation. Patients may benefit from insights into how to better manage conditions like inflammatory bowel disease (IBD) through improved understanding of immune regulation. The approach includes laboratory experiments and analysis of immune cell behavior in the gut.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing and treating inflammatory bowel diseases and other related conditions.
How similar studies have gone: Other research has shown promising results in understanding immune regulation in the gut, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Zhou, Wenqing — Weill Medical Coll of Cornell Univ
- Study coordinator: Zhou, Wenqing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.