Understanding how a mother's weight affects breast milk and her child's health

MOM2CHild Study: Leveraging systems biology toward discoveries in Maternal Obesity, Milk, and Translation To Child Health

NIH-funded research University of Cincinnati · NIH-11127378

This project aims to understand how a mother's weight during pregnancy might change her breast milk and affect her child's health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Cincinnati NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-11127378 on NIH RePORTER

What this research studies

Breastfeeding is important for infant health, but we don't fully understand how it works or what might affect milk quality. Many pregnant women experience obesity, which can impact breastfeeding and potentially lead to health issues for their children, including a higher risk of childhood obesity. This project will use advanced methods to look closely at how a mother's weight and related health conditions might change her breast milk and influence her child's well-being. By taking a comprehensive look at these connections, we hope to gain a clearer picture of this important relationship.

Who could benefit from this research

Good fit: Ideal participants would be pregnant women with obesity and their children, likely followed from the third trimester through early childhood.

Not a fit: Patients who are not pregnant, do not have obesity, or are not breastfeeding may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could help us better support breastfeeding mothers and develop strategies to improve child health outcomes, especially for children whose mothers experienced obesity.

How similar studies have performed: While many smaller studies have hinted at connections between maternal obesity and milk components, this project uses a novel, comprehensive 'systems biology' approach to define these impacts more convincingly.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.