Understanding How a Hormone Controls Ovarian Egg Development
Anti-Mullerian Hormone Actions to Control Primate Folliculogenesis
This research explores how a hormone called Anti-Müllerian hormone (AMH) guides the growth of eggs in the ovary, aiming to improve fertility for women.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-11175998 on NIH RePORTER |
What this research studies
We are learning more about how Anti-Müllerian hormone (AMH) works in the ovary to control the development of egg follicles. Our work shows that AMH helps early-stage follicles grow while preventing later-stage follicles from maturing too quickly. By carefully adjusting AMH levels, we hope to improve how follicles grow and mature, which could lead to healthier eggs. We are also looking into the specific cellular processes that AMH influences, including how cells use energy and manage oxygen levels, to better understand its role in ovarian function.
Who could benefit from this research
Good fit: This foundational research is relevant to women experiencing fertility challenges related to ovarian function and egg development.
Not a fit: Patients whose fertility issues are unrelated to ovarian follicle development or AMH actions may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to improve ovarian function and enhance female fertility for those struggling to conceive.
How similar studies have performed: Previous work has shown that AMH plays a critical role in ovarian development, and modulating its actions has shown promise in improving follicle growth in laboratory settings.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Krieg, Adam J — Oregon Health & Science University
- Study coordinator: Krieg, Adam J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.