Understanding how a heart hormone receptor works
Structural Dynamics and Regulatory Mechanisms of Atrial Natriuretic Peptide Receptor
['FUNDING_R01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11028284
This study is looking at how a hormone called atrial natriuretic peptide (ANP) interacts with its receptor in the body, which is important for keeping your heart and blood pressure healthy, and it could help us find new ways to treat heart disease and high blood pressure.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11028284 on ClinicalTrials.gov |
What this research studies
This research investigates the atrial natriuretic peptide (ANP) and its receptor, which play crucial roles in heart health and blood pressure regulation. The study aims to uncover the structural changes that occur in the receptor when it binds to ANP, which is important for understanding how this hormone helps maintain cardiovascular balance. By using advanced techniques, researchers will explore the mechanisms that govern the receptor's function and its impact on heart and kidney health. This knowledge could lead to new treatments for conditions like hypertension and heart disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with hypertension or heart-related conditions who may benefit from new therapeutic approaches targeting the ANP pathway.
Not a fit: Patients without cardiovascular issues or those not affected by hypertension may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for heart disease and hypertension by enhancing our understanding of how the ANP receptor functions.
How similar studies have performed: Previous research has shown promising results in understanding similar hormonal pathways, suggesting that this approach could yield valuable insights.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HUANG, XIN-YUN — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: HUANG, XIN-YUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.