Understanding how a cellular process can help yeast live longer

Discovering how autophagy is sufficient to extend yeast replicative lifespan

['FUNDING_R01'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11060925

This study is looking at how a process that helps cells clean up damaged parts can help yeast live longer, and by figuring this out, researchers hope to find ways that might help people age healthier too.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorWEILL MEDICAL COLL OF CORNELL UNIV (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11060925 on ClinicalTrials.gov

What this research studies

This research investigates the role of autophagy, a cellular process that helps remove damaged components, in extending the lifespan of yeast cells. By studying how various interventions, such as medications and dietary changes, affect yeast's ability to replicate, the researchers aim to uncover the molecular mechanisms behind aging. The findings could provide insights into how similar processes might be applied to other organisms, including humans, to promote healthier aging. Patients may benefit from understanding these mechanisms as they could lead to new anti-aging therapies.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in aging and longevity, particularly those with age-related conditions.

Not a fit: Patients with acute or terminal conditions unrelated to aging may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to breakthroughs in anti-aging therapies that improve healthspan and longevity in humans.

How similar studies have performed: Other research has shown promising results in extending lifespan through similar cellular mechanisms, indicating potential for success in this area.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.