Understanding how a brain region influences thinking and memory
Behavioral and mechanistic dissection of a cognitive thalamo-cortical network
This study looks at how two important parts of the brain work together to help with attention and memory, especially in people with cognitive disorders like schizophrenia, to find new ways to improve their thinking and behavior.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts University Boston NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10813778 on NIH RePORTER |
What this research studies
This research investigates the interactions between the mediodorsal thalamus and the prefrontal cortex, which are crucial for cognitive functions such as attention and memory. By studying these brain regions, the research aims to uncover how they work together to enhance relevant cognitive activities while suppressing irrelevant ones. The approach involves testing specific hypotheses about how these brain areas communicate and influence behavior, particularly in the context of cognitive disorders like schizophrenia. Patients may benefit from insights gained about these mechanisms, potentially leading to new therapeutic strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing cognitive disorders, particularly those with attention deficits or schizophrenia.
Not a fit: Patients with purely physical health issues unrelated to cognitive function may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for cognitive disorders, enhancing memory and attention in affected patients.
How similar studies have performed: Previous research has shown promising results in understanding thalamic-cortical interactions, suggesting that this approach could yield valuable insights.
Where this research is happening
Boston, United States
- Tufts University Boston — Boston, United States (Active)
Researchers
- Principal investigator: Halassa, Michael M — Tufts University Boston
- Study coordinator: Halassa, Michael M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.