Understanding HIV's Effects on the Brain

HIV Neurobehavioral Research Center

['FUNDING_P30'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11062386

This project helps us learn more about how HIV affects the brain and nervous system, and how to better prevent, diagnose, and treat these issues for people living with HIV.

Quick facts

Phase['FUNDING_P30']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded)
Locations1 site (LA JOLLA, UNITED STATES)
Trial IDNIH-11062386 on ClinicalTrials.gov

What this research studies

For over two decades, this center has been a leader in understanding how HIV impacts the brain and nervous system. We support various studies, from basic science to clinical trials, to improve care for people with HIV. Our work includes exploring how HIV persists in the brain, ways to potentially eliminate it, and the connection between gut health and brain disorders in HIV. We also focus on understanding and addressing common issues like depression and memory problems in people with HIV. This is achieved by using data and samples from a large registry of individuals.

Who could benefit from this research

Good fit: People living with HIV, especially those experiencing or at risk for brain-related symptoms like memory problems or depression, are the focus of this research.

Not a fit: Patients without HIV or those whose conditions are unrelated to HIV's effects on the brain and nervous system would not directly benefit from this specific research.

Why it matters

Potential benefit: This work could lead to new ways to prevent, diagnose, and treat brain and nervous system problems, including depression and cognitive issues, for people living with HIV.

How similar studies have performed: This center has a long history of advancing understanding in neuroHIV, building on two decades of successful research in the field.

Where this research is happening

LA JOLLA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome, Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome, Acquired Immunodeficiency Syndrome Virus, Affective Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.