Understanding HIV prevention for incarcerated individuals in Zambia

Prison PrEP Values Adherence and Implementation in Lusaka (PrEVAIL)

['FUNDING_R21'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10819509

This study is looking at how to best provide HIV prevention medication, called PrEP, to people in prison in Lusaka, Zambia, who are at high risk for HIV, and it wants to understand how they use it while in jail and after they get out.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MARYLAND BALTIMORE (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-10819509 on ClinicalTrials.gov

What this research studies

This research investigates how to effectively provide pre-exposure prophylaxis (PrEP) to incarcerated individuals in Lusaka, Zambia, who are at high risk for HIV. It aims to understand the patterns of PrEP uptake, adherence, and persistence among these individuals during their time in prison and as they transition back to the community. By examining their perceptions of HIV risk and behaviors, the study seeks to optimize the timing and delivery of PrEP as part of a comprehensive prevention strategy. The research builds on previous studies focused on health services for incarcerated populations in sub-Saharan Africa.

Who could benefit from this research

Good fit: Ideal candidates for this research are incarcerated individuals in Zambia who are at risk for HIV.

Not a fit: Patients who are not incarcerated or who do not have a risk of HIV infection may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce HIV transmission rates among incarcerated individuals and improve their overall health outcomes.

How similar studies have performed: Previous studies have shown success in implementing HIV prevention strategies in incarcerated populations, indicating that this approach has potential.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.