Understanding HIV-2 latency and how to reverse it
HIV-2 latency and its reversal
This study is looking at how HIV-2, a type of virus that can cause AIDS, acts differently from HIV-1, especially how it can hide in the body, and it's inviting people with HIV-2 to help find new ways to tackle the virus.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10909884 on NIH RePORTER |
What this research studies
This research investigates the unique characteristics of HIV-2, a virus that can lead to AIDS, and how it behaves differently from HIV-1. The study focuses on understanding the latency of HIV-2, which means how the virus can hide in the body and evade treatment. By examining the biological features of HIV-2, particularly how it integrates into human DNA and interacts with immune cells, the researchers aim to identify new strategies to effectively eliminate the virus. Participants with HIV-2 are being recruited to contribute to this important research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with HIV-2 who are willing to participate in longitudinal studies.
Not a fit: Patients with HIV-1 or those who do not have HIV may not benefit from this specific research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that effectively eradicate HIV-2 from the body, improving health outcomes for patients.
How similar studies have performed: While research on HIV-1 latency has shown promise, this specific focus on HIV-2 is relatively novel and untested.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Tsibris, Athe M. — Brigham and Women's Hospital
- Study coordinator: Tsibris, Athe M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.