Understanding hip joint changes after surgery for developmental dysplasia
Official title: Longitudinal Biomechanics and Patient-Reported Outcomes after Periacetabular Osteotomy for Developmental Dysplasia of the Hip
Funded at Washington University · NIH-11010160 · Data updated 2026-11-12
This study is looking at how a hip surgery called periacetabular osteotomy (PAO) helps people with hip problems feel better and move easier during their first year after the operation, by checking how their hips change and how that relates to their pain and daily activities.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | February 10, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $30,323 |
| NIH project number | 3R01AR081881-02S1 |
| Project ID | NIH-11010160 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents and young adults diagnosed with developmental dysplasia of the hip who are scheduled to undergo periacetabular osteotomy.
✕Less likely to help
Patients who have already undergone PAO or those with other unrelated hip conditions may not benefit from this research.
What this research studies
This research investigates how a specific surgical procedure, called periacetabular osteotomy (PAO), affects the biomechanics of the hip joint in patients with developmental dysplasia of the hip (DDH). By analyzing changes in hip geometry and biomechanics, the study aims to understand how these changes relate to patients' reported levels of pain, function, and quality of life during the first year after surgery. The research utilizes patient-reported outcome measures (PROMs) to assess improvements and identify factors that may influence recovery. This comprehensive approach seeks to enhance surgical care and outcomes for individuals undergoing PAO.
Why it matters
Potential benefit: If successful, this research could lead to improved surgical techniques and rehabilitation strategies that enhance recovery and quality of life for patients with developmental dysplasia of the hip.
How similar studies have gone: Previous research has shown promising results in understanding the biomechanics of hip disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Harris, Michael D — Washington University
- Study coordinator: Harris, Michael D
Related research
Other NIH-funded projects on the same topics.
-
Using MRI to measure brain oxygen levels as an early sign of small vessel disease in the brain
This study is looking at how measuring oxygen levels in the brain with MRI can help spot early signs of small vessel disease, which is linked to memory problems and dementia, especially Alzheimer's, so if you're at risk due to age or high blood pressure, you might be able to participate in MRI scans to learn more about
-
Advanced Methods & Modeling for Better Patient Care
A funding opportunity focused on developing new modeling methods to improve health care for patients through better data use and analytics.
-
Advanced methods and modeling for health research at Washington University
A health research grant at Washington University funds new modeling methods to support future patient-focused studies.
-
Center for Research in Emerging Infectious Diseases: Epidemiology, Surveillance and Pathogenesis
A NIH program will study and monitor emerging viruses from the Midwest U.S. and three Asian sites to understand how they spread and affect people.
-
How Poverty and the Environment Affect Heart Disease in Haiti and Beyond
This grant studies how poverty-related factors like food insecurity, stress, and pollution contribute to heart disease and aims to follow a large group of adults to better understand and prevent the disease.
-
Wearable tech to track blood loss during childbirth
A wearable device monitors cardiovascular signals to detect postpartum hemorrhage early so clinicians can act quickly to protect mothers.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.