Understanding High Blood Pressure, Treatment Goals, and Dementia Risk in US Veterans
Official title: Hypertension, Blood Pressure Targets, and Alzheimer’s Disease and Dementia Risk and Disparities among Nationally Representative US Veterans
Funded at University of California, San Francisco · NIH-11197583 · Data updated 2026-11-12
This project looks at how high blood pressure and its treatment might affect the risk of Alzheimer's disease and related dementias in US veterans.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 30, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $792,967 |
| NIH project number | 5R01AG085481-02 |
| Project ID | NIH-11197583 on NIH RePORTER |
Who could benefit from this research
✓Could help
This project focuses on understanding health information from US veterans, particularly those aged 65 and older, who have a history of hypertension and other military-related exposures.
✕Less likely to help
Patients who are not US veterans or whose health information is not part of the Veterans Health Administration records would not directly benefit from this specific data analysis.
What this research studies
We are exploring how high blood pressure and its treatment goals are connected to the risk of developing Alzheimer's disease and related dementias in US veterans. Veterans often face unique health challenges, including a higher chance of conditions like traumatic brain injury, PTSD, and depression, which can also influence dementia risk. By carefully examining health records from the Veterans Health Administration, we hope to understand these connections better. This includes looking at how these factors might differ among various racial, ethnic, and geographic groups of veterans.
Why it matters
Potential benefit: This work could help identify better ways to manage blood pressure to reduce the risk of Alzheimer's disease and related dementias for veterans.
How similar studies have gone: Previous research suggests that hypertension is a major risk factor for dementia and that managing blood pressure may help reduce this risk, making this a promising area of inquiry.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Yaffe, Kristine — University of California, San Francisco
- Study coordinator: Yaffe, Kristine
Related research
Other NIH-funded projects on the same topics.
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Hypertension, Blood Pressure Targets, and Alzheimer’s Risk and Disparities in US Veterans
This project looks at how blood pressure control and its targets relate to Alzheimer's and related dementia risk in diverse U.S. veterans.
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Investigating the link between hypertension and Alzheimer's risk in US veterans
This study is looking at how managing high blood pressure might affect the chances of U.S. veterans developing Alzheimer's and other types of dementia, especially for those who might be at greater risk due to their background or military experiences.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.