Understanding high blood pressure after preeclampsia
Mechanisms of post-preeclampsia hypertension
This study is looking at how having preeclampsia during pregnancy might affect women's blood pressure and heart health later on, especially focusing on certain immune cells that could play a role in these changes, with the goal of finding better ways to help women who are at risk of high blood pressure after preeclampsia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11015060 on NIH RePORTER |
What this research studies
This research investigates the long-term effects of preeclampsia on women's blood pressure and vascular health after pregnancy. It focuses on how certain immune cells, specifically T cells, may contribute to persistent hypertension and vascular changes that occur in women who have experienced preeclampsia. By using animal models, the study aims to uncover the mechanisms behind these changes and identify potential targets for treatment. The findings could lead to better management strategies for women at risk of hypertension following preeclampsia.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who have experienced preeclampsia during pregnancy and are concerned about their long-term cardiovascular health.
Not a fit: Patients who have not experienced preeclampsia or those with unrelated hypertension conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and preventive measures for women at risk of hypertension after preeclampsia.
How similar studies have performed: Previous research has shown that immune responses play a role in hypertension, suggesting that this approach may yield valuable insights, although the specific mechanisms in post-preeclampsia hypertension are still being explored.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Biwer, Lauren Alysse — Yale University
- Study coordinator: Biwer, Lauren Alysse
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.