Understanding hidden cholera infections and their impact on prevention efforts
Official title: The role of unobserved cholera: implications for prevention and control
Funded at Temple Univ of the Commonwealth · NIH-10896119 · Data updated 2026-11-12
This study is looking into how many people might have cholera without showing any symptoms, especially in places where the disease is common, to help find better ways to prevent and control outbreaks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Temple Univ of the Commonwealth NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $108,000 |
| NIH project number | 5K22AI168389-02 |
| Project ID | NIH-10896119 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals living in cholera-endemic regions, particularly those who may experience mild or asymptomatic infections.
✕Less likely to help
Patients who are not in cholera-endemic areas or those who have already been diagnosed with severe cholera may not benefit from this research.
What this research studies
This research investigates the role of unobserved cholera infections, which often go undetected due to mild or asymptomatic cases. By analyzing clinical and serological data from various populations, the study aims to estimate how many cholera infections are unreported and how this affects transmission and outbreak control. The research will focus on understanding the differences in infection patterns across different regions, particularly in areas where cholera is endemic. This knowledge could help improve strategies for cholera prevention and control.
Why it matters
Potential benefit: If successful, this research could lead to more effective cholera prevention strategies, potentially reducing the incidence of cholera outbreaks.
How similar studies have gone: Previous studies have shown that unobserved infections significantly contribute to cholera transmission, indicating that this research builds on established findings.
Where this research is happening
-
Temple Univ of the Commonwealth
Philadelphia, United States Active
Researchers
- Principal investigator: Wiens, Kirsten E — Temple Univ of the Commonwealth
- Study coordinator: Wiens, Kirsten E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.