Understanding HER2+ breast cancer in diverse populations
Official title: Her2 status of breast cancer in diverse populations: improving genetic prediction and understanding molecular correlates
Funded at University of California at Davis · NIH-11078209 · Data updated 2026-11-12
This study is looking at how genetics and other factors affect HER2-positive breast cancer in Hispanic/Latina and Asian American women, with the goal of better understanding cancer risks and treatment results, and it invites patients to share their genetic samples and health information to help improve care for everyone.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $395,010 |
| NIH project number | 5R01CA273313-03 |
| Project ID | NIH-11078209 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include women from Hispanic/Latina and Asian American backgrounds who have been diagnosed with breast cancer.
✕Less likely to help
Patients who do not have breast cancer or do not belong to the targeted racial/ethnic groups may not benefit from this research.
What this research studies
This research investigates the genetic and molecular factors associated with HER2-positive breast cancer, particularly in Hispanic/Latina and Asian American women. It aims to improve the prediction of cancer risk and treatment outcomes by studying how these factors differ across various racial and ethnic groups. By analyzing genetic data and tumor characteristics, the research seeks to address disparities in breast cancer treatment and outcomes. Patients may be involved in providing genetic samples and health information to help advance this important work.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of breast cancer risk and tailored treatments for diverse populations.
How similar studies have gone: Previous studies have shown promising results in understanding HER2+ breast cancer in diverse populations, indicating that this research builds on established findings.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Fejerman, Laura — University of California at Davis
- Study coordinator: Fejerman, Laura
Related research
Other NIH-funded projects on the same topics.
-
HER2 in breast cancer among diverse communities
This project looks at genetic and molecular factors linked to HER2-positive breast cancer in women from Hispanic/Latina, Asian American/Pacific Islander, Indigenous American, African, and other diverse backgrounds.
-
Understanding HER2-positive breast cancer in diverse communities
This project looks at genetic and tumor features that may explain why HER2-positive breast cancer is more common in Hispanic/Latina, Asian American/Pacific Islander, Indigenous, and other diverse groups.
-
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This study is testing a new imaging technology that helps doctors check the edges of tissue removed during breast surgery in real-time, aiming to reduce the chances of needing extra surgeries and improve outcomes for patients.
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This study is looking at how breast cancer-related lymphedema affects nurses who have survived breast cancer, focusing on their symptoms and daily challenges, to better understand their needs and improve support for them.
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Aimed at helping doctors in Nigeria follow international guideline-based breast cancer care to improve outcomes for women with breast cancer.
-
Genomic study to understand how genetics and epigenetics shape triple-negative breast cancer in African ancestry
This study looks at how inherited genes and gene activity affect triple-negative breast cancer in people of African ancestry to better understand why outcomes can be worse.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.