Understanding heart rhythm problems after a heart attack
Ventricular arrhythmias and mechanisms of parasympathetic dysfunction following myocardial infarction
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10870018
This study is looking at how heart rhythm problems, especially after a heart attack, are linked to the nervous system and aims to find new ways to help prevent these issues and keep your heart healthy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10870018 on ClinicalTrials.gov |
What this research studies
This research investigates how heart rhythm issues, specifically ventricular arrhythmias, occur following a heart attack and the role of the body's nervous system in this process. It aims to explore the mechanisms behind reduced parasympathetic function, which is crucial for heart health, and how this dysfunction contributes to dangerous heart rhythms. By studying the interactions between sympathetic and parasympathetic signals in the heart, the research seeks to identify new therapeutic approaches to prevent recurrent arrhythmias and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a myocardial infarction and are at risk for ventricular arrhythmias.
Not a fit: Patients who have not had a heart attack or do not have a history of ventricular arrhythmias may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that reduce the risk of dangerous heart rhythms and improve the quality of life for patients with a history of heart attacks.
How similar studies have performed: Previous research has shown that understanding the autonomic nervous system's role in heart rhythm disorders can lead to significant advancements in treatment, although this specific approach is still being explored.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VASEGHI, MARMAR — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: VASEGHI, MARMAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.