Understanding heart problems in people with HIV
Cell-Type Specific Mechanisms of HIV Cardiomyopathy
This study looks at how HIV and its treatments can affect the heart and lead to heart problems, with the hope of finding better ways to help people living with HIV stay heart-healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10991361 on NIH RePORTER |
What this research studies
This research investigates how HIV and its treatments affect different cell types in the heart, particularly focusing on the mechanisms that lead to heart failure in individuals living with HIV. By examining the impact of chronic inflammation and immune dysregulation associated with HIV, the study aims to uncover the specific pathways that contribute to cardiovascular diseases in this population. The goal is to develop targeted therapies that can improve heart health for those affected by HIV-related cardiac issues.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 50 and older who are living with HIV and have cardiovascular disease or are at high risk for heart-related complications.
Not a fit: Patients who do not have HIV or those without any cardiovascular issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new, tailored treatments that significantly improve heart health in people living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding cardiovascular issues in HIV patients, but this specific approach focusing on cell-type mechanisms is relatively novel.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Chi, Neil C — University of California, San Diego
- Study coordinator: Chi, Neil C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.