Understanding heart problems in Duchenne and Becker muscular dystrophy
Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials
This study is looking at heart problems that can happen in people with Duchenne and Becker muscular dystrophy to find better ways to check heart health and track how the disease changes over time, which will help improve treatments and future drug trials for those affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11014435 on NIH RePORTER |
What this research studies
This research focuses on the heart complications associated with Duchenne and Becker muscular dystrophy (DMD/BMD), which can lead to severe health issues and early death. The study aims to identify new ways to measure heart health and disease progression in patients, using advanced imaging techniques and clinical data collection. By creating a detailed registry of patients and their heart health, the research seeks to improve the design of future drug trials and enhance treatment options for these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Duchenne or Becker muscular dystrophy, particularly those experiencing heart complications.
Not a fit: Patients without a diagnosis of Duchenne or Becker muscular dystrophy are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and treatment strategies for heart issues in patients with DMD and BMD.
How similar studies have performed: Previous research has shown promise in understanding heart complications in muscular dystrophies, but this specific approach is novel and aims to fill significant gaps in current knowledge.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Soslow, Jonathan Harvey — Vanderbilt University Medical Center
- Study coordinator: Soslow, Jonathan Harvey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.