Understanding heart mechanics in patients with dilated cardiomyopathy
Precision Medicine for Dilated Cardiomyopathy—Novel Assessment of Cardiac Mechanics via Speckle Tracking Echocardiography to Identify Early Phenotypes
This study is looking at how we can better understand heart function in people with dilated cardiomyopathy (DCM) by using special ultrasound techniques, especially for those who might be at risk due to their genes, so we can catch any early signs of heart issues and tailor treatments just for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10436899 on NIH RePORTER |
What this research studies
This research investigates how specific heart mechanics can be assessed in patients with dilated cardiomyopathy (DCM) using advanced echocardiography techniques. By analyzing cardiac function in individuals who may be genetically predisposed to DCM, the study aims to identify early signs of the disease before significant heart damage occurs. Participants will undergo echocardiographic evaluations to gather detailed data on their heart's performance, which will be correlated with genetic testing results. This approach seeks to enhance early diagnosis and personalized treatment strategies for those at risk of developing heart failure.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with dilated cardiomyopathy and their family members who may also be at risk due to genetic factors.
Not a fit: Patients with dilated cardiomyopathy that is clearly diagnosed and managed without genetic considerations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of dilated cardiomyopathy, potentially improving patient outcomes.
How similar studies have performed: Other research has shown promise in using advanced echocardiographic techniques to assess heart conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Hershberger, Ray E. — Ohio State University
- Study coordinator: Hershberger, Ray E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.