Understanding heart, lung, blood, and sleep conditions in people with HIV
Official title: Links between Cardiovascular disease, Lung disease, and Obstructive sleep apnea in HIV: Understanding complex patients
Funded at University of Washington · NIH-11111418 · Data updated 2026-11-12
This project aims to better understand how heart, lung, blood, and sleep conditions affect people living with HIV, including the role of new risk factors like COVID-19 and different medications.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 12, 2014 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $667,628 |
| NIH project number | 5R01HL126538-07 |
| Project ID | NIH-11111418 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients living with HIV who have or are at risk for cardiovascular, lung, blood, or sleep disorders are the focus of this research.
✕Less likely to help
Patients without HIV or those not experiencing these specific co-occurring conditions may not directly benefit from this particular research.
What this research studies
People living with HIV often experience heart, lung, blood, and sleep disorders, and this project wants to learn more about why. We are looking at how these conditions interact with each other and with factors like new medications, COVID-19, and social circumstances. By using a large database of over 37,000 people with HIV from multiple sites, we can identify patterns and improve screening methods for conditions like obstructive sleep apnea. Our goal is to find better ways to care for complex patients and improve their health outcomes.
Why it matters
Potential benefit: This work could lead to improved screening, diagnosis, and treatment strategies for heart, lung, blood, and sleep disorders in people with HIV.
How similar studies have gone: Previous work by this team successfully established methods for classifying heart attack types in people with HIV, providing a strong foundation for this expanded project.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Crane, Heidi M. — University of Washington
- Study coordinator: Crane, Heidi M.
Related research
Other NIH-funded projects on the same topics.
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Finding which people with sleep apnea are at higher risk of heart disease
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Using machine learning to find sleep apnea patients at risk for heart disease
This study is looking at how advanced computer technology can help find people with obstructive sleep apnea who might be more likely to develop heart problems, so that doctors can tailor treatments to each person's needs and improve their care.
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The link between obstructive sleep apnea, gut bacteria, and heart disease
This study is looking at how obstructive sleep apnea might change the bacteria in your gut and how that could affect your heart health, and it invites patients to help by sharing samples or information to better understand these connections.
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Mechanisms of sex-specific responses to sleep apnea therapies
A research project at NYU School of Medicine is exploring how men and women may respond differently to treatments for obstructive sleep apnea and related heart risk.
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Deep learning to predict obstruction site and guide sleep apnea treatment
A patient-focused project uses snoring sounds and AI to predict where your airway collapses during sleep and to guide personalized treatments.
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Personalized DISE-guided surgery for sleep apnea in children with Down syndrome
A personalized surgical approach guided by DISE sleep-endoscopy is being tested to better treat sleep apnea in children with Down syndrome who don’t always improve after standard surgery.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.