Understanding heart issues in women who had preeclampsia

Identifying Inflammatory and Endothelial Mechanisms promoting Cardiac Deformation in Women with a History of Preeclampsia

NIH-funded research The Christ Hospital · NIH-11032931

This study is looking at how having preeclampsia during pregnancy might affect a woman's heart health later on, and it aims to find out what causes these potential issues so that better ways to prevent and treat them can be developed.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionThe Christ Hospital NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-11032931 on NIH RePORTER

What this research studies

This research investigates the long-term cardiovascular risks faced by women who have experienced preeclampsia during pregnancy. It aims to identify the inflammatory and endothelial mechanisms that contribute to heart and vascular problems in these women, using a biorepository of samples to measure specific biomarkers. By analyzing these biomarkers in relation to heart function and vascular health, the study seeks to uncover the underlying causes of cardiovascular disease in this population. The findings could lead to better prevention and treatment strategies for affected women.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have had preeclampsia and are currently 2-10 years postpartum.

Not a fit: Patients who have not experienced preeclampsia or are currently pregnant may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of cardiovascular risks in women with a history of preeclampsia.

How similar studies have performed: Previous research has indicated that similar approaches to studying cardiovascular risks in women with pregnancy complications have shown promising results.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.