Understanding heart issues in women who had preeclampsia
Official title: Identifying Inflammatory and Endothelial Mechanisms promoting Cardiac Deformation in Women with a History of Preeclampsia
Funded at The Christ Hospital · NIH-11032931 · Data updated 2026-11-12
This study is looking at how having preeclampsia during pregnancy might affect a woman's heart health later on, and it aims to find out what causes these potential issues so that better ways to prevent and treat them can be developed.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | The Christ Hospital NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | January 1, 2025 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $99,150 |
| NIH project number | 1R03HL177034-01 |
| Project ID | NIH-11032931 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who have had preeclampsia and are currently 2-10 years postpartum.
✕Less likely to help
Patients who have not experienced preeclampsia or are currently pregnant may not benefit from this research.
What this research studies
This research investigates the long-term cardiovascular risks faced by women who have experienced preeclampsia during pregnancy. It aims to identify the inflammatory and endothelial mechanisms that contribute to heart and vascular problems in these women, using a biorepository of samples to measure specific biomarkers. By analyzing these biomarkers in relation to heart function and vascular health, the study seeks to uncover the underlying causes of cardiovascular disease in this population. The findings could lead to better prevention and treatment strategies for affected women.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cardiovascular risks in women with a history of preeclampsia.
How similar studies have gone: Previous research has indicated that similar approaches to studying cardiovascular risks in women with pregnancy complications have shown promising results.
Where this research is happening
-
The Christ Hospital
Cincinnati, United States Active
Researchers
- Principal investigator: Quesada, Odayme — The Christ Hospital
- Study coordinator: Quesada, Odayme
Related research
Other NIH-funded projects on the same topics.
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A digital health approach uses AI to spot early warning signs of preeclampsia and gestational hypertension from pregnancy data, so clinicians can tailor care for pregnant people.
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Folate Receptor Beta and its Role in Preeclampsia
This study explores how a protein called folate receptor beta on placental immune cells may drive or worsen preeclampsia in pregnancy, with hopes of finding new ways to prevent or treat the condition.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.