Understanding heart injury caused by sepsis
Informing best practices for evaluation and treatment of myocardial injury during sepsis
This study looks at how sepsis can harm the heart and aims to find the best ways to treat patients with this condition, especially by checking if blood thinners can help improve their recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Massachusetts Med Sch Worcester NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project ID | NIH-10916493 on NIH RePORTER |
What this research studies
This research investigates how sepsis, a severe infection that can lead to organ dysfunction, affects the heart muscle, causing myocardial injury. It aims to identify the best practices for evaluating and treating patients with this condition by analyzing existing health records from large healthcare systems. The study will explore various treatment pathways and assess the effectiveness of blood thinners in improving outcomes for these patients. By gathering and analyzing this data, the research seeks to provide actionable insights for clinicians.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with sepsis who also exhibit signs of myocardial injury.
Not a fit: Patients who do not have sepsis or myocardial injury are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved evaluation and treatment strategies for patients suffering from myocardial injury during sepsis.
How similar studies have performed: Previous research has shown that analyzing electronic health records can effectively identify treatment patterns and improve patient outcomes in similar conditions.
Where this research is happening
Worcester, United States
- Univ of Massachusetts Med Sch Worcester — Worcester, United States (Active)
Researchers
- Principal investigator: Walkey, Allan J. — Univ of Massachusetts Med Sch Worcester
- Study coordinator: Walkey, Allan J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.