Understanding heart health risks in women after pregnancy complications
Official title: Arterial Stiffness and Wave Reflection: Physiological Contributors to CVD after Adverse Pregnancy Outcomes
Funded at University of Michigan at Ann Arbor · NIH-10906743 · Data updated 2026-11-12
This study is looking at how problems during pregnancy, like high blood pressure and early delivery, might affect a woman's heart health later on, especially for those who are not yet in menopause, and it aims to find ways to spot who might be at risk for heart issues in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $692,228 |
| NIH project number | 5R01HL167841-02 |
| Project ID | NIH-10906743 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women who have had adverse pregnancy outcomes, such as hypertensive disorders or preterm births.
✕Less likely to help
Patients who have not experienced any adverse pregnancy outcomes may not benefit from this research.
What this research studies
This research investigates how adverse pregnancy outcomes, such as high blood pressure during pregnancy and preterm birth, can lead to increased risks of cardiovascular disease in women later in life. It focuses on identifying sensitive measures of heart health, particularly in premenopausal women, to better predict who may develop cardiovascular issues after experiencing these complications. The study will analyze data from over 4,000 women, looking at their pregnancy histories and cardiovascular risk factors to find patterns that could indicate future heart problems.
Why it matters
Potential benefit: If successful, this research could lead to improved screening and prevention strategies for cardiovascular disease in women who have experienced adverse pregnancy outcomes.
How similar studies have gone: Previous studies have shown promising results in understanding vascular function changes during and after pregnancies with adverse outcomes, indicating that this research builds on established findings.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Lane, Abbi Danielle — University of Michigan at Ann Arbor
- Study coordinator: Lane, Abbi Danielle
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.