Understanding heart health in rural communities

Epidemiologic Determinants of Cardiac Structure and Function in Rural Residents: RURAL ECHO

NIH-funded research Duke University · NIH-11010840

This study is looking at heart health in adults living in rural areas of the South, especially in Appalachia and the Mississippi Delta, to find out who might be at risk for heart problems before they even feel sick, so we can create better ways to help them stay healthy.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11010840 on NIH RePORTER

What this research studies

This research investigates the high rates of cardiovascular disease among adults living in rural areas of the US South, particularly in the Appalachia and Mississippi Delta regions. By using echocardiography, the study aims to noninvasively assess the structure and function of the heart in these populations, identifying individuals at risk for heart failure even before symptoms appear. The research will analyze various biological, social, and phenotypic factors that contribute to heart health disparities, with the goal of developing interventions to reduce the burden of cardiovascular disease. Participants will be part of a unique cohort that seeks to understand and address these health challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults living in rural areas of the Appalachia and Mississippi Delta regions who may be at risk for cardiovascular disease.

Not a fit: Patients living outside of rural areas or those without risk factors for cardiovascular disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier interventions for heart disease, improving health outcomes for rural residents.

How similar studies have performed: Previous research has shown success in using echocardiography to identify cardiac issues in various populations, making this approach promising for the targeted rural communities.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.