Understanding heart healing and blood vessel growth in mammals
Official title: Temporospatial Single-Cell Characterization of Angiogenesis and Myocardial Regeneration in Small and Large Mammals
Funded at Stanford University · NIH-10975031 · Data updated 2026-11-12
This study is exploring how the heart can heal and grow new blood vessels after an injury, looking at both small and large animals, to find ways to help people recover better from heart problems.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | August 10, 2023 |
| Project end | August 9, 2025 |
| Funding year | 2024 |
| Award (this year) | $83,932 |
| NIH project number | 5F32HL170741-02 |
| Project ID | NIH-10975031 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from ischemic heart disease or related heart conditions.
✕Less likely to help
Patients with non-ischemic heart conditions or those who are not experiencing heart failure may not benefit from this research.
What this research studies
This research investigates how the heart can regenerate and form new blood vessels after injury, focusing on both small and large mammals. It utilizes a cutting-edge imaging technique called CODEX to analyze the cellular processes involved in heart repair at a single-cell level. By studying the differences in regenerative capabilities between neonatal mammals and adult humans, the research aims to uncover potential pathways that could enhance heart recovery in patients. The project involves collaboration with a multidisciplinary team of experts in cardiology and cell biology.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve heart regeneration and recovery for patients with ischemic heart disease.
How similar studies have gone: Previous research has shown promising results in understanding heart regeneration in animal models, but this specific approach using CODEX is relatively novel.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Elde, Stefan — Stanford University
- Study coordinator: Elde, Stefan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.