Understanding heart function issues in young people with chronic kidney disease
Advancing the Approach to Subclinical Diastolic Dysfunction in Youth with Chronic Kidney Disease
This study is looking at how chronic kidney disease affects the hearts of young people and aims to find early signs of heart problems, while also testing if certain medications can help improve heart function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-11037903 on NIH RePORTER |
What this research studies
This research investigates how chronic kidney disease (CKD) affects heart function in young patients, particularly focusing on subclinical diastolic dysfunction, which can lead to serious heart problems later in life. The study aims to identify early signs of heart issues using advanced echocardiographic techniques and to explore whether medications can help reverse these early changes. By applying patient-oriented research methods, the project seeks to improve the understanding and treatment of cardiovascular disease in youth with CKD.
Who could benefit from this research
Good fit: Ideal candidates for this research are youth aged 0 to 21 years who have been diagnosed with chronic kidney disease.
Not a fit: Patients without chronic kidney disease or those over the age of 21 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for heart problems in young patients with chronic kidney disease.
How similar studies have performed: Previous research in adults with chronic kidney disease has shown promising results in understanding and treating cardiovascular issues, suggesting that this approach may also be beneficial in pediatric populations.
Where this research is happening
Chicago, United States
- Lurie Children's Hospital of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Kula, Alexander James — Lurie Children's Hospital of Chicago
- Study coordinator: Kula, Alexander James
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.