Understanding Heart Failure with Preserved Ejection Fraction in California's Central Valley
A prospective multiethnic HFpEF cohort from California's Central Valley
This project gathers detailed health information from a diverse group of patients in California's Central Valley who have a specific type of heart failure called HFpEF, to better understand their condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project ID | NIH-11138564 on NIH RePORTER |
What this research studies
We are creating a special group of patients with heart failure where the heart still pumps blood well, known as HFpEF, from the diverse communities in California's Central Valley. Our team uses advanced imaging, including a new total-body PET scan, to look closely at how different organs and body systems are connected in these patients. By studying this diverse group, we hope to uncover unique patterns related to metabolism and inflammation that contribute to HFpEF. This detailed information will help us understand why this condition affects people differently and identify key factors that drive the disease.
Who could benefit from this research
Good fit: Ideal candidates for this type of research would be multiethnic patients living in California's Central Valley who have been diagnosed with heart failure with preserved ejection fraction (HFpEF).
Not a fit: Patients without heart failure with preserved ejection fraction or those outside the California Central Valley catchment area would not directly benefit from participation in this specific cohort.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of heart failure with preserved ejection fraction, potentially guiding the development of more personalized and effective treatments for patients.
How similar studies have performed: While the specific combination of deep phenotyping and advanced PET scanning on this diverse population is novel, the investigative team has a strong history of participating in large-scale research networks that collect and analyze patient data.
Where this research is happening
Davis, United States
- University of California at Davis — Davis, United States (Active)
Researchers
- Principal investigator: Chiamvimonvat, Nipavan — University of California at Davis
- Study coordinator: Chiamvimonvat, Nipavan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.