Understanding heart failure with preserved ejection fraction
Mayo Clinic HeartShare Clinical Center
This study is looking into how heart failure with preserved ejection fraction (HFpEF) works and aims to find better ways to diagnose and treat it, so that patients can receive more personalized care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10892172 on NIH RePORTER |
What this research studies
This research aims to explore the underlying mechanisms of heart failure with preserved ejection fraction (HFpEF) and to develop new diagnostic and treatment strategies. The Mayo Clinic will collaborate with other centers to gather clinical data and utilize advanced machine learning techniques to identify different phenotypes of HFpEF. By analyzing various biological and clinical factors, the research seeks to uncover specific pathways that contribute to this condition, which could lead to more personalized therapies for patients. The study will also focus on improving patient recruitment and retention to ensure robust data collection.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with heart failure with preserved ejection fraction.
Not a fit: Patients with heart failure with reduced ejection fraction or other unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted treatments for patients suffering from heart failure with preserved ejection fraction.
How similar studies have performed: Previous research has shown promise in using machine learning to identify phenotypes in various diseases, suggesting that this approach could be beneficial in understanding HFpEF.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Borlaug, Barry a. — Mayo Clinic Rochester
- Study coordinator: Borlaug, Barry a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.