Understanding heart failure with preserved ejection fraction

Wake Forest Atrium HeartShare Clinical Center

['FUNDING_U01'] · WAKE FOREST UNIVERSITY HEALTH SCIENCES · NIH-10890085

This study is looking at heart failure with preserved ejection fraction (HFpEF) to better understand the condition and find new ways to treat it, and it's for anyone affected by HFpEF or interested in learning more about it.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorWAKE FOREST UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (WINSTON-SALEM, UNITED STATES)
Trial IDNIH-10890085 on ClinicalTrials.gov

What this research studies

This research focuses on Heart Failure with Preserved Ejection Fraction (HFpEF), a common and serious condition affecting many individuals in the U.S. The project aims to create a large cohort of HFpEF patients and controls to conduct in-depth analysis and characterization of the disease. By utilizing advanced methodologies, including comprehensive phenotyping, the research seeks to uncover new mechanisms and potential treatment targets for HFpEF. The team at Wake Forest is experienced in recruiting diverse patient populations, ensuring a broad representation in their findings.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals diagnosed with Heart Failure with Preserved Ejection Fraction.

Not a fit: Patients with other forms of heart failure or those without a diagnosis of heart failure may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of effective treatments for HFpEF, improving outcomes for patients suffering from this condition.

How similar studies have performed: Previous research efforts in understanding HFpEF have shown limited success, making this approach both novel and crucial for advancing treatment options.

Where this research is happening

WINSTON-SALEM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.