Understanding heart failure with preserved ejection fraction
Mentoring in Patient-Oriented and Translational HFpEF Research
This study is looking into how obesity and inflammation affect heart failure with preserved ejection fraction (HFpEF) to help improve understanding and treatment for people living with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10864007 on NIH RePORTER |
What this research studies
This research focuses on heart failure with preserved ejection fraction (HFpEF), a condition affecting many patients worldwide. It aims to explore the underlying mechanisms and contributing factors of HFpEF, particularly the role of obesity and systemic inflammation. The research involves clinical and translational approaches, including multi-cohort studies and prospective examinations of obesity's impact on heart function. By training new researchers in this field, the project seeks to enhance understanding and treatment options for patients with HFpEF.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with heart failure, particularly those with preserved ejection fraction and associated conditions like obesity.
Not a fit: Patients with heart failure who have reduced ejection fraction may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients suffering from heart failure with preserved ejection fraction.
How similar studies have performed: Previous research has shown promise in understanding heart failure mechanisms, but this specific focus on HFpEF and its subphenotypes is relatively novel.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Ho, Jennifer E — Beth Israel Deaconess Medical Center
- Study coordinator: Ho, Jennifer E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.