Understanding heart failure subtypes to improve treatment options
HeartShare: Next-Generation Phenomics to Define Heart Failure Subtypes and Treatment Targets - Clinical Centers
This study is looking at heart failure with preserved ejection fraction (HFpEF) to better understand how it affects people and find out which treatments might work best for different groups, so we can help improve care for those living with this condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10890079 on NIH RePORTER |
What this research studies
This research focuses on heart failure, particularly a subtype known as heart failure with preserved ejection fraction (HFpEF), which affects a significant number of adults in the U.S. The project aims to create a large cohort of patients with HFpEF and other related conditions to deeply analyze their health data and identify specific subgroups that may respond better to targeted therapies. By collecting comprehensive clinical and socioeconomic data, the research seeks to uncover the underlying mechanisms of HFpEF and improve treatment strategies for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 years old with heart failure, particularly those with preserved ejection fraction.
Not a fit: Patients with heart failure who do not have preserved ejection fraction or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients suffering from heart failure.
How similar studies have performed: Previous research has shown promise in using deep phenotyping to identify effective treatment strategies for heart failure subtypes, indicating that this approach may yield valuable insights.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Chirinos Medina, Julio Alonso — University of Pennsylvania
- Study coordinator: Chirinos Medina, Julio Alonso
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.