Understanding heart failure progression in African Americans
Quantifying cardiac structure and function to define the progression to hear failure in African Americans
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10886956
This study is looking at how health issues like high blood pressure and diabetes can lead to heart failure, especially in African Americans, and it will involve some tests to better understand these connections.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10886956 on ClinicalTrials.gov |
What this research studies
This research investigates how various health conditions and inflammation contribute to heart failure, particularly in African Americans who are disproportionately affected. It aims to identify the mechanisms behind heart failure with preserved ejection fraction (HFpEF), which is prevalent in this population. By examining factors like hypertension, diabetes, and physical inactivity, the study seeks to understand how these conditions lead to cardiac dysfunction and ultimately heart failure. Patients may undergo echocardiograms and other assessments to help define these relationships.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals at risk for heart failure, particularly those with conditions like hypertension, diabetes, or obesity.
Not a fit: Patients who are not African American or those without risk factors for heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for heart failure in African Americans.
How similar studies have performed: Previous research has shown promising results in understanding heart failure mechanisms, particularly in populations with higher prevalence rates, indicating that this approach may yield valuable insights.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHAH, AMIL M — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: SHAH, AMIL M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.