Understanding heart failure in people with HIV in South Africa
Clinical and immunologic factors underlying heart failure with preserved ejection fraction among persons with HIV in South Africa
['FUNDING_R01'] · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · NIH-10915005
This study is looking at how living with HIV affects heart health, especially for people in South Africa who have heart failure with preserved ejection fraction, to better understand their unique health challenges and improve care for them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HENNEPIN HEALTHCARE RESEARCH INSTITUTE (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10915005 on ClinicalTrials.gov |
What this research studies
This research investigates the clinical and immunologic factors that contribute to heart failure with preserved ejection fraction (HFpEF) among individuals living with HIV in South Africa. It aims to identify how chronic HIV disease affects heart health, particularly focusing on the unique risk factors present in this population. By examining the relationship between HIV and heart failure, the study seeks to characterize different clinical profiles based on co-existing health conditions. This approach will help in understanding the specific challenges faced by patients in low-to-middle income countries.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV in South Africa, particularly those experiencing or at risk for heart failure.
Not a fit: Patients who are not living with HIV or those who do not reside in South Africa may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for heart failure in people living with HIV.
How similar studies have performed: While research has focused on ischemic heart disease in HIV patients, this specific investigation into HFpEF in a South African context is relatively novel.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- HENNEPIN HEALTHCARE RESEARCH INSTITUTE — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAKER, JASON V — HENNEPIN HEALTHCARE RESEARCH INSTITUTE
- Study coordinator: BAKER, JASON V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus