NIH-funded research R01 grant

Understanding heart failure in Hispanic and Latino populations

Official title: Proteomic profiling of heart failure in Hispanics/Latinos

Funded at University of Texas Hlth Sci Ctr Houston · NIH-11072700 · Data updated 2026-11-12

This study is looking at how certain biological factors might lead to heart failure, especially in Hispanic and Latino people who often deal with obesity and diabetes, by examining specific proteins in their bodies to find out more about heart health and improve treatments.

More Heart Failure research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston
NIH-funded
Lab location1 site (Houston, United States)
Project startMay 20, 2025
Project endFebruary 28, 2029
Funding year2025
Award (this year)$816,079
NIH project number1R01HL173837-01A1
Project IDNIH-11072700 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include Hispanic and Latino individuals who are at risk for heart failure due to obesity, diabetes, or other related health conditions.

Less likely to help

Patients who do not identify as Hispanic or Latino or those without risk factors for heart failure may not benefit from this research.

What this research studies

This research investigates the biological factors contributing to heart failure, particularly in Hispanic and Latino individuals who often face higher rates of obesity and diabetes. By analyzing protein biomarkers through advanced proteomic profiling, the study aims to uncover the molecular pathways that lead to heart dysfunction and heart failure. The research will utilize data from a large community health study focused on Hispanic/Latino health, aiming to identify specific proteins that could indicate heart failure risk. This approach seeks to address the lack of effective therapies for heart failure with preserved ejection fraction in these populations.

Why it matters

Potential benefit: If successful, this research could lead to the identification of new biomarkers and therapeutic targets for preventing heart failure in Hispanic and Latino patients.

How similar studies have gone: Previous research has shown promise in identifying biomarkers for heart failure in diverse populations, but this specific focus on Hispanic/Latino individuals is relatively novel.

Where this research is happening

  • University of Texas Hlth Sci Ctr Houston
    Houston, United States
    Active

Researchers

  • Principal investigator: Yu, Bing — University of Texas Hlth Sci Ctr Houston
  • Study coordinator: Yu, Bing

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.