Understanding heart failure in diverse populations

Wake Forest Atrium HeartShare Clinical Center

NIH-funded research Wake Forest University Health Sciences · NIH-11144871

This study is looking at heart failure with preserved ejection fraction (HFpEF) to find out more about how it affects women and non-Hispanic Black individuals, and it aims to gather detailed health information from a diverse group of heart failure patients to help create better treatments for everyone.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11144871 on NIH RePORTER

What this research studies

This research focuses on heart failure with preserved ejection fraction (HFpEF), a condition that significantly impacts women and non-Hispanic Black individuals. The project aims to uncover biological signals associated with HFpEF to develop targeted interventions. It involves creating a large registry of heart failure patients and a deep phenotyping cohort to gather detailed health information. The study emphasizes the importance of diversity in participant recruitment to ensure the findings are applicable to a broader population.

Who could benefit from this research

Good fit: Ideal candidates for this research include women and non-Hispanic Black individuals who are experiencing heart failure with preserved ejection fraction.

Not a fit: Patients who do not have heart failure or those from populations already well-represented in existing studies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments and interventions for heart failure, particularly in underrepresented populations.

How similar studies have performed: Previous research has shown success in understanding heart failure through diverse participant engagement, but this specific approach is novel in its focus on inclusivity and deep phenotyping.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.