Understanding heart failure in children using blood samples
Investigations of Pathologic Remodeling Using Pediatric Heart Failure Serum
This study is looking at how heart failure happens in children with a specific heart condition called dilated cardiomyopathy, to find new ways to help them feel better and improve their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10747399 on NIH RePORTER |
What this research studies
This research investigates the mechanisms of heart failure in pediatric patients by analyzing serum samples from children with dilated cardiomyopathy. The study aims to identify unique cellular processes that contribute to heart failure in this age group, which may differ from adults. By integrating patient samples with laboratory models, researchers hope to uncover new therapeutic targets that could improve treatment outcomes for young patients. The research also emphasizes mentorship for junior faculty and fellows, fostering the next generation of researchers in this critical field.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with dilated cardiomyopathy or other forms of heart failure.
Not a fit: Patients with heart failure due to causes unrelated to pediatric conditions or those over 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve the health and quality of life for children suffering from heart failure.
How similar studies have performed: Previous research has shown promise in understanding heart failure mechanisms in adults, but this approach focusing specifically on pediatric patients is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Sucharov, Carmen C — University of Colorado Denver
- Study coordinator: Sucharov, Carmen C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.