Understanding heart failure and its different types using advanced technology

CHIcago Center for Accelerating nextGen Omics, deep phenotyping, and data science in Heart Failure (CHICAGO-HF)

['FUNDING_U01'] · NORTHWESTERN UNIVERSITY AT CHICAGO · NIH-10890012

This study is looking at heart failure with preserved ejection fraction (HFpEF) to better understand how it affects people and to find more personalized treatments, using advanced imaging and tests to get a closer look at the heart and related health issues.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorNORTHWESTERN UNIVERSITY AT CHICAGO (nih funded)
Locations1 site (CHICAGO, UNITED STATES)
Trial IDNIH-10890012 on ClinicalTrials.gov

What this research studies

This research focuses on heart failure with preserved ejection fraction (HFpEF), a condition that affects many individuals and currently lacks effective treatments. By utilizing advanced techniques such as magnetic resonance imaging (MRI) and biopsies, the study aims to deeply analyze the heart's structure and function, as well as the various health issues that may accompany heart failure. The goal is to gather comprehensive data on patients to better understand the disease and develop personalized treatment strategies. This approach emphasizes precision medicine, moving away from generic treatments to tailored therapies based on individual patient characteristics.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with heart failure with preserved ejection fraction.

Not a fit: Patients with heart failure types other than preserved ejection fraction or those under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective, personalized treatments for patients suffering from heart failure.

How similar studies have performed: Previous research has shown promise in using advanced phenotyping techniques to improve understanding and treatment of heart failure, indicating that this approach could yield significant insights.

Where this research is happening

CHICAGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.