Understanding heart development and congenital heart disease in children
Cardiovascular Development Data Resource Center (CDDRC)
This study is looking into the genetic reasons behind congenital heart disease in kids, hoping to find out what causes these heart problems so that we can better understand and help those affected.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10903877 on NIH RePORTER |
What this research studies
This research focuses on congenital heart disease (CHD), which affects about 1% of children born in the U.S. each year. It utilizes advanced genomic sequencing techniques to explore the genetic and epigenetic factors contributing to heart development and malformations. By analyzing data from various model organisms and children with CHD, the project aims to uncover the underlying causes of these conditions. The findings will be organized and made accessible through a dedicated data hub, facilitating further research and understanding.
Who could benefit from this research
Good fit: Ideal candidates for this research include children diagnosed with congenital heart disease and their families.
Not a fit: Patients without congenital heart disease or those over the age of 21 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for children with congenital heart disease.
How similar studies have performed: Previous research utilizing genomic sequencing in similar contexts has shown promising results in understanding congenital heart disease.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Yost, H. Joseph — University of Utah
- Study coordinator: Yost, H. Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.