Understanding heart complications from COVID-19
Official title: Mechanisms of atherosclerotic cardiovascular complications in COVID19
Funded at New York University School of Medicine · NIH-10911267 · Data updated 2026-11-12
This study is looking at how COVID-19 might cause heart issues like heart attacks and strokes even after people have recovered from the virus, by checking heart tissue from patients to see how the virus affects inflammation and heart health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $768,169 |
| NIH project number | 5R01HL165258-03 |
| Project ID | NIH-10911267 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have recovered from COVID-19 and are experiencing cardiovascular symptoms or have a history of heart disease.
✕Less likely to help
Patients who have not had COVID-19 or do not have cardiovascular issues may not benefit from this research.
What this research studies
This research investigates how COVID-19 may lead to serious heart problems, such as heart attacks and strokes, even after recovery from the virus. By examining tissue from patients who had COVID-19, the researchers are looking for viral material in heart plaques and studying how it affects inflammation and disease progression. They use advanced techniques like single cell RNA sequencing to identify specific receptors that the virus interacts with in the heart. The goal is to uncover the mechanisms behind these cardiovascular complications to improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for heart complications in COVID-19 survivors.
How similar studies have gone: Other research has indicated potential links between viral infections and cardiovascular complications, suggesting that this approach may yield valuable insights.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Giannarelli, Chiara — New York University School of Medicine
- Study coordinator: Giannarelli, Chiara
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.