Understanding heart changes in children with Tetralogy of Fallot
Right Ventricular Remodeling in Tetralogy of Fallot
['FUNDING_FELLOWSHIP'] · UNIVERSITY OF PENNSYLVANIA · NIH-10897232
This study looks at how the hearts of children with Tetralogy of Fallot change over time, especially the right ventricle, to help doctors find out which kids might need extra care after their surgery.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-10897232 on ClinicalTrials.gov |
What this research studies
This research investigates how the heart changes in children with Tetralogy of Fallot (ToF), a common congenital heart defect. It focuses on the right ventricle, which can become enlarged and dysfunctional even after surgical repair. By using advanced imaging techniques like cardiovascular magnetic resonance (CMR), the study aims to identify which patients are at risk for complications related to these heart changes. The goal is to improve monitoring and treatment strategies for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with Tetralogy of Fallot and have undergone surgical repair.
Not a fit: Patients who do not have Tetralogy of Fallot or are older than 11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and outcomes for children with Tetralogy of Fallot by identifying those at risk for serious heart complications.
How similar studies have performed: Previous research has shown success in using advanced imaging techniques to assess heart conditions, indicating that this approach may yield valuable insights.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: THOMPSON, ELIZABETH WALKER — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: THOMPSON, ELIZABETH WALKER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.