Understanding heart biology and disease through cell surface proteins and sugars
Harnessing Glycoproteomics and Glycomics to Understand Cardiac Biology and Disease
This study is looking at tiny parts of heart cells to find new ways to improve treatments for heart failure, helping doctors take better care of patients with heart problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11030294 on NIH RePORTER |
What this research studies
This research focuses on using advanced mass spectrometry and bioinformatics to explore the role of cell surface proteins and sugars in heart health and disease. By analyzing small samples of human heart cells, the team aims to identify specific markers that can help in the development of better treatments for heart failure. The study also seeks to improve the quality of stem cell-derived heart cells for both research and clinical use, ultimately enhancing patient care. The innovative tools developed in this research could lead to more precise monitoring and treatment strategies for patients with cardiac conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with advanced heart failure or those undergoing stem cell therapy for cardiac conditions.
Not a fit: Patients with non-cardiac related health issues or those not experiencing heart failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for patients suffering from heart failure.
How similar studies have performed: Other research has shown promise in using similar mass spectrometry and bioinformatics approaches to advance our understanding of cardiac biology.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Gundry, Rebekah L. — University of Nebraska Medical Center
- Study coordinator: Gundry, Rebekah L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.