Understanding Heart and Lung Problems from World Trade Center Dust
World Trade Center Particulate Matter Induced Cardiorespiratory and Vascular Dysfunction: a MultiOmic Approach
This work explores how exposure to dust from the World Trade Center disaster may lead to heart and lung issues in affected individuals.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11076617 on NIH RePORTER |
What this research studies
Many people exposed to World Trade Center dust on 9/11 developed various health problems, including respiratory and cardiovascular conditions. This project aims to understand why these heart and lung issues, known as cardiorespiratory and vascular dysfunction, develop in WTC responders and survivors. We are looking closely at how the dust affects the body at a molecular level, including changes in the lungs and blood vessels. By uncovering the underlying causes, we hope to find better ways to diagnose and treat these conditions early.
Who could benefit from this research
Good fit: This research is relevant for individuals who were exposed to World Trade Center particulate matter and have developed or are at risk for cardiorespiratory and vascular dysfunction.
Not a fit: Patients whose health conditions are unrelated to World Trade Center particulate matter exposure may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to earlier diagnosis and more effective treatments for heart and lung problems linked to World Trade Center dust exposure.
How similar studies have performed: While the link between WTC exposure and various morbidities is established, this multi-omic approach to cardiorespiratory and vascular dysfunction is a novel investigation into its pathogenesis.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Nolan, Anna — New York University School of Medicine
- Study coordinator: Nolan, Anna
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.