Understanding hearing problems in Fragile X Syndrome
Myelination Deficits Underlying Auditory Issues in Fragile X Syndrome
This study is looking at how problems with brain wiring might affect how people with Fragile X Syndrome hear and understand sounds, using mice to learn more about these issues.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma State University Stillwater NIH-funded |
| Lab location | 1 site (Stillwater, United States) |
| Project ID | NIH-10622759 on NIH RePORTER |
What this research studies
This research investigates how myelination deficits in the brain may contribute to auditory processing issues in individuals with Fragile X Syndrome, a genetic condition associated with autism. By studying mice with Fragile X Syndrome, researchers will analyze the structure and function of auditory pathways in the brainstem, focusing on how these pathways process sound information. The study employs various techniques, including anatomical measurements and non-invasive brain response recordings, to explore the underlying mechanisms of these auditory difficulties. The goal is to better understand how myelination affects hearing and auditory behavior in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Fragile X Syndrome or related auditory processing disorders.
Not a fit: Patients without Fragile X Syndrome or those who do not experience auditory processing issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for auditory processing issues in patients with Fragile X Syndrome.
How similar studies have performed: Previous research has indicated that myelination plays a critical role in auditory processing, suggesting that this approach may yield valuable insights.
Where this research is happening
Stillwater, United States
- Oklahoma State University Stillwater — Stillwater, United States (Active)
Researchers
- Principal investigator: Mccullagh, Elizabeth Anne — Oklahoma State University Stillwater
- Study coordinator: Mccullagh, Elizabeth Anne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.