Understanding Healthy Brain Development in Children

3/24 Healthy Brain and Child Development National Consortium

NIH-funded research Children's Hosp of Philadelphia · NIH-11141218

This project aims to understand how genes and early life experiences shape brain development in children from before birth through age 10.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionChildren's Hosp of Philadelphia NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11141218 on NIH RePORTER

What this research studies

This project brings together many researchers to learn how a child's genes and early life experiences, both good and bad, affect their brain development. We want to create a clear picture of how children's brains typically grow during their first 10 years. To do this, we will follow 7,200 mothers and their babies across the United States, using advanced brain imaging and other tools to track their development. This will help us understand how things like substance exposure, stress, or other health conditions during pregnancy and early childhood might impact a child's future.

Who could benefit from this research

Good fit: Ideal candidates are pregnant mothers and their infants who are willing to participate in a long-term follow-up until their child is 10 years old.

Not a fit: Patients who are not pregnant or do not have young children within the specified age range would not directly benefit from participating in this particular project.

Why it matters

Potential benefit: This work could help us better understand how to support healthy brain development and prevent long-term problems in children.

How similar studies have performed: While individual aspects of child development have been studied, this project is novel in its large scale, harmonized approach, and comprehensive tracking of neurodevelopmental trajectories across many sites.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.