Understanding Healthy Brain and Child Development

21/24 Healthy Brain and Child Development National Consortium

NIH-funded research University of Wisconsin-Madison · NIH-11141592

This project aims to understand how early life experiences and genes influence brain and child development in thousands of mothers and their babies across the United States.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison NIH-funded
Lab location1 site (Madison, United States)
Project IDNIH-11141592 on NIH RePORTER

What this research studies

Our brains and how we grow are shaped by a mix of our genes and the world around us. This project looks closely at how experiences very early in life, even before birth, can affect a child's development, including things like exposure to certain substances, stress, or a parent's health. We are following 7,200 mothers and their babies across the country for 10 years to create a detailed picture of healthy development. We use advanced brain imaging like MRI and EEG, along with behavioral tests and biological samples, to understand these important connections.

Who could benefit from this research

Good fit: Mothers and their infants, from pregnancy through the first 10 years of life, who are enrolled at one of the 27 participating sites across the US, are ideal candidates for this project.

Not a fit: Patients not enrolled in this specific project or those outside the age range of 0-10 years old would not directly benefit from participation.

Why it matters

Potential benefit: If successful, this work could help us better understand how to support healthy brain and child development and identify ways to prevent problems caused by early life challenges.

How similar studies have performed: While the overall approach of studying gene-environment interactions is established, this project is a novel, large-scale effort to create a comprehensive, harmonized dataset of neurodevelopmental trajectories across the US.

Where this research is happening

Madison, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.