Understanding health outcomes in children after experiencing trauma
Clinical and biologic health trajectories after early life adversity
This study looks at how tough experiences in childhood, like abuse or neglect, can impact kids' mental and physical health, and it aims to find ways to help those affected by understanding their unique genetic and biological responses to trauma.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10872114 on NIH RePORTER |
What this research studies
This research investigates how early life adversities, such as child abuse and neglect, affect the mental and physical health of children. It aims to identify predictors of health outcomes by examining genetic factors and biological responses to trauma. The study employs a multimodal approach, integrating clinical assessments and genomic data to uncover the complex relationships between childhood trauma and long-term health. By understanding these connections, the research seeks to develop targeted interventions to improve health trajectories for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research include children and adolescents who have experienced abuse or neglect.
Not a fit: Patients who have not experienced any form of early life adversity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved interventions that enhance the health and well-being of children who have experienced trauma.
How similar studies have performed: Other research has shown success in understanding the impacts of childhood trauma on health, making this approach both relevant and promising.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Chaiyachati, Barbara Hirschman — Children's Hosp of Philadelphia
- Study coordinator: Chaiyachati, Barbara Hirschman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.