Understanding health conditions in individuals with Down syndrome
Data Management and Portal for the INCLUDE (DAPI) Project
This study is looking at the health of people with Down syndrome to understand why they are more likely to get some diseases, like Alzheimer's and heart problems, but less likely to get others, and it aims to find ways to improve care for them and everyone else.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10899515 on NIH RePORTER |
What this research studies
This research investigates the unique health profile of individuals with Down syndrome, focusing on their predisposition to certain diseases like Alzheimer's and congenital heart disease while being protected from others. It aims to uncover the mechanisms behind these differences, including genetic, epigenetic, and environmental factors. By analyzing the diverse health outcomes in this population, the project seeks to improve understanding and treatment of related conditions in both individuals with Down syndrome and the general population.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with Down syndrome, particularly those experiencing or at risk for Alzheimer's disease and other related conditions.
Not a fit: Patients without Down syndrome or those not affected by Alzheimer's disease or related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment strategies for individuals with Down syndrome and related health conditions.
How similar studies have performed: Previous research has shown promising results in understanding health disparities in Down syndrome, indicating that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Resnick, Adam Cain — Children's Hosp of Philadelphia
- Study coordinator: Resnick, Adam Cain
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.