Understanding gut bacteria and the protective lining of the digestive tract
Exploring the complex interactions between gut microbes and mucus
This research helps us learn how the helpful bacteria in our gut interact with the protective mucus lining, which is important for our overall health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project ID | NIH-11180435 on NIH RePORTER |
What this research studies
Our digestive system contains many different helpful bacteria that keep us healthy. A key part of this system is the mucus lining, which acts as a protective barrier and also feeds these bacteria. We want to understand how these bacteria use mucus for food and communication, and how they might even encourage the body to make more mucus. By understanding these complex relationships, we hope to uncover new ways to support gut health.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation at this stage, but future studies building on this work may seek individuals with various gut health conditions.
Not a fit: Patients seeking immediate new treatments or direct clinical interventions would not find direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to new ways to improve gut health and address digestive disorders by better understanding the gut's natural defenses.
How similar studies have performed: While the general interaction between gut bacteria and mucus is known, the specific details of how they communicate and influence each other are largely new and unexplored.
Where this research is happening
Charleston, United States
- Medical University of South Carolina — Charleston, United States (Active)
Researchers
- Principal investigator: Engevik, Melinda Anne — Medical University of South Carolina
- Study coordinator: Engevik, Melinda Anne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.