Understanding Gulf War Veterans' Illness through a Humanized Mouse Model
Official title: Humanized Mouse Model of Gulf War Veterans' Illness
Funded at John D Dingell VA Medical Center · NIH-11249109 · Data updated 2026-11-12
This study is looking at the health problems that Gulf War veterans face by creating a special mouse model to help understand their symptoms better, with the goal of finding out what causes these issues and how to improve treatments for those affected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | John D Dingell VA Medical Center NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| NIH project number | 5I21BX005850-03 |
| Project ID | NIH-11249109 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Gulf War veterans experiencing chronic, unexplained health issues related to their service.
✕Less likely to help
Patients who are not Gulf War veterans or do not exhibit symptoms related to Gulf War Veterans' Illness may not benefit from this research.
What this research studies
This research investigates Gulf War Veterans' Illness (GWVI) by developing a humanized mouse model to better understand the complex symptoms experienced by veterans. The study aims to identify the underlying pathological mechanisms and potential toxicant exposures that contribute to these persistent health issues. By mimicking the biological responses of Gulf War veterans, researchers hope to gain insights into the disease processes and improve diagnostic criteria. This approach may lead to more effective treatments and interventions for affected individuals.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for Gulf War Veterans suffering from unexplained illnesses.
How similar studies have gone: While research on Gulf War Veterans' Illness is ongoing, this specific approach using a humanized mouse model is relatively novel and has not been extensively tested.
Where this research is happening
-
John D Dingell VA Medical Center
Detroit, United States Active
Researchers
- Principal investigator: Angoa-Perez, Mariana — John D Dingell VA Medical Center
- Study coordinator: Angoa-Perez, Mariana
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.