Understanding Gonorrhea and Antibiotic Resistance in Men on PrEP
Antimicrobial resistance in Neisseria gonorrhoeae among men on PrEP in Vietnam
This project aims to better understand how gonorrhea is becoming resistant to antibiotics in men who are taking medication to prevent HIV in Vietnam.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11137752 on NIH RePORTER |
What this research studies
Gonorrhea is a common infection that is becoming harder to treat because it's developing resistance to antibiotics, which is a global health concern. This project will look closely at how often antibiotic-resistant gonorrhea occurs in men who have sex with men and are using HIV prevention medication (PrEP) in Vietnam. Researchers will also track how often treatments fail, particularly for throat infections, and use genetic tools to understand how the bacteria are spreading and changing. This work is embedded within an existing HIV PrEP program, leveraging regular testing for gonorrhea.
Who could benefit from this research
Good fit: Ideal candidates for this type of research would be men who have sex with men, are on PrEP, and live in Vietnam, as the study focuses on this specific population.
Not a fit: Patients not in the specific demographic of men on PrEP in Vietnam, or those without gonorrhea, would not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could help doctors better treat gonorrhea and prevent the spread of untreatable infections, especially for men on PrEP.
How similar studies have performed: While the general problem of antibiotic resistance is known, this specific focus on men on PrEP in Vietnam using genomic epidemiology is a targeted and important area of ongoing investigation.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Adamson, Paul C — University of California Los Angeles
- Study coordinator: Adamson, Paul C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.