Understanding genetics to predict kidney disease and hypertension risks
Genetics of CKD and Hypertension-Risk Prediction and Drug Response in the MVP
This study is looking at how your genes might help doctors predict your risk of chronic kidney disease and high blood pressure, so they can offer you personalized care sooner and help slow down any problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Health Administration NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10863818 on NIH RePORTER |
What this research studies
This research investigates how genetic factors can help predict the risk of chronic kidney disease (CKD) and hypertension in patients. By generating Genetic Risk Scores (GRS) based on extensive genetic data, the study aims to improve the prediction of CKD progression and treatment responses. Patients with a higher genetic risk may receive tailored interventions earlier, potentially slowing disease progression. The research will also explore the use of polygenic risk scores to enhance prediction accuracy further.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are at risk for or currently have chronic kidney disease or hypertension.
Not a fit: Patients with no genetic predisposition to chronic kidney disease or hypertension may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for chronic kidney disease and hypertension, ultimately improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using genetic risk scores for predicting various health conditions, indicating that this approach may be effective.
Where this research is happening
Nashville, United States
- Veterans Health Administration — Nashville, United States (Active)
Researchers
- Principal investigator: Hung, Adriana — Veterans Health Administration
- Study coordinator: Hung, Adriana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.